(Reuters) -The U.S. Food and Drug Administration is probing the death of a patient who developed harmful antibodies after taking Takeda Pharmaceuticals' blood disorder therapy, the health regulator said on Friday.
The pediatric patient died about 10 months after starting Takeda's drug Adzynma as a preventive therapy, the agency said.
The child had congenital thrombotic thrombocytopenic purpura (cTTP), an inherited condition that causes blood clots in small vessels and can lead to organ damage.
The FDA said the child developed antibodies that blocked the activity of ADAMTS13, an enzyme critical for blood clotting.
Takeda did not immediately respond to Reuters request for comment.
Adzynma, approved in 2023 as the first therapy for cTTP, replaces the ADAMTS13 protein to help prevent dangerous blood clots.
The agency added it has received multiple postmarketing reports of patients developing neutralizing antibodies to ADAMTS13 after treatment with Adzynma.
(Reporting by Kamal Choudhury in Bengaluru; Editing by Vijay Kishore)
LATEST POSTS
- 1
Who is Adm. Frank 'Mitch' Bradley and what does he have to do with the Venezuela boat strikes? - 2Well known Tea Brands for Each Tea Sweetheart
- 3The Best Music Collections of the 10 years
- 4First Greenland, now Iceland? Annexation joke by Trump ally gets frosty response in the Arctic nation.
- 5Instructions to Pick the Right Dental Embed Trained professional: An Exhaustive Aide
- The Job of Attorneys: It is Important to Comprehend When Legitimate Help
- 6 Savvy Locks for Lofts
- Fundamental Home Exercise center Hardware: Amplify Your Exercises
- UK to hold fresh pork, other affected Spanish products at border amid African swine fever outbreak
- Schools to start reopening after Nigeria mass abduction
- Ethiopian earthquakes and volcanic eruptions: earth scientist explains the link
- Is 'Veronica Mars' about to be your new binge-watch? It's now streaming on Netflix.
- The most effective method to Remain Ahead in the Most recent Advanced Patterns with a Web based Advertising Degree
- France will build a new aircraft carrier as it increases defense spending
